ROCKVILLE, MD, October 3, 2007—EntreMed, Inc. (NASDAQ: ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and inflammatory diseases, today announced it has been named one of Maryland’s fastest growing companies in Deloittes’ Technology Fast 50 program. This represents the second consecutive year EntreMed has received this prestigious award. The program is presented by Deloitte and sponsored by WilmerHale, NASDAQ, and SmartCEO Magazine.
The Technology Fast 50 program is a ranking of the 50 fastest growing technology, media, telecommunications and life sciences companies throughout 16 regions in the United States and Canada. The Company has also been entered for consideration in the North American Technology Fast 500 program, a ranking of the 500 fastest growing technology, media, telecommunications and life sciences companies.
James S. Burns, EntreMed’s President and CEO, commented, “We are once again pleased to receive this award from Deloitte and to be acknowledged as a prominent life sciences growth company. EntreMed continues to focus its resources and scientific energies on the development of small molecule drugs that target the inhibition of multiple cellular pathways important in cancer and inflammatory diseases. Our recent progress has positioned us as a solid Phase 2 oncology drug development company with three clinical development programs. We look forward to continuing our progress on these programs.”

About EntreMed
EntreMed, Inc. is a clinical-stage pharmaceutical company developing therapeutic candidates primarily for the treatment of cancer and inflammation. Panzem® NCD (2-methoxyestradiol or 2ME2) is currently in multiple Phase 2 clinical trials for cancer. MKC-1, an oral cell-cycle regulator, is in multiple Phase 1 and 2 studies for cancer. ENMD-1198, a novel tubulin-binding agent, is in Phase 1 studies in advanced cancers. Panzem® is also in preclinical development for rheumatoid arthritis, and ENMD-2076, a dual-acting Aurora-angiogenesis inhibitor, is in preclinical development for cancer. EntreMed’s goal is to develop and commercialize new compounds based on the Company’s expertise in angiogenesis, cell-cycle regulation and inflammation – processes vital to the treatment of cancer and other diseases, such as rheumatoid arthritis. Additional information about EntreMed is available on the Company’s web site at www.entremed.com and in various filings with the Securities and Exchange Commission.

Forward Looking Statements
This release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act with respect to the outlook for expectations for future financial or business performance (including the timing of royalty revenues and future R&D expenditures), strategies, expectations and goals. Forward-looking statements are subject to numerous assumptions, risks and uncertainties, which change over time. Forward-looking statements speak only as of the date they are made, and no duty to update forward-looking statements is assumed. Actual results could differ materially from those currently anticipated due to a number of factors, including those set forth in Securities and Exchange Commission filings under “Risk Factors,” including risks relating to the need for additional capital and the uncertainty of additional funding; variations in actual sales of Thalomid®, risks associated with the Company’s product candidates; the early-stage products under development; results in preclinical models are not necessarily indicative of clinical results, uncertainties relating to preclinical and clinical trials; success in the clinical development of any products; dependence on third parties; future capital needs; and risks relating to the commercialization, if any, of the Company’s proposed products (such as marketing, safety, regulatory, patent, product liability, supply, competition and other risks).

About Deloitte
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